The use of flesh-flies (Diptera, subfamily Sarcophagidae) for large-scale monitoring of several pollutant groups (heavy metals, respirable asbestos fibres, residues of organochlorine pesticides and polychlorinated biphenyls) was studied. The experimental territory comparised South and Central Moravia of the Czech Republic, which is known to be the crossway of Ponto-Pannonian, West-Carpathian and East-Hercynian districts. The results show that widely distributed flesh-flies represent a suitable insect taxocoenosis for biomonitoring of pollutants in different kinds of habitats.