Kysuce represent the region with typical kopanitse-dispersed settlement. Originally forest landscape has been changed years ago, the forests were grub, new settlements were built and pastures, meadows and fields were created. The transformational changes cause that the land ceases to cultivate, face the overgrowing meadows and pastures by non-forest tree and shrub vegetation in different successional stages. We evaluated the use of agricultural landscapes based on CORINE land cover databases (2006) and databases DATAcube of Statistical Office of Slovak republic (1996 – 2014). Changes of use of agricultural landscape were evaluated as the development of land resources through changes in its structure (development of changes in land areas). These changes were assessed in terms of representation of the two main categories - agricultural soil and non-agricultural soil. The aim of this paper was to assess the condition of land use on the basis of soil -substrate complexes (SSC) and evaluate changes in the use of agricultural and non-agricultural soils for the period 1996 – 2014. The area of agricultural soil was reduced by 850 ha. The proportion of the total area is 0,89 %. Arable land has the largest cover in the SSC 26 (714 ha) and SSC 24 (708 ha). Mosaic of fields, meadows and permanent crops cover the largest area, 2,491 ha (SSC 6).