Ecological indicators can be seen as measures providing the information about the complexity of nature. As the human demand on nature services is rapidly increasing, the indicators constitute an important tool for the assessment of sustainability of economic systems. Healthy ecosystems are prerequisite not only for the sustainable human society but also for the conservation of biodiversity. However, currently the indicators of ecosystem services are not developed sufficiently to be incorporated into the decision-making and into the systems of national accounts. The set of ecological indicators has been proposed in different world’s regions, but they often suffer from data deficiency. Existing ecological and biodiversity indicators which express the state of nature reliably and credibly are irreplaceable tools for designing the future fate of biodiversity.